| CASE REPORT |
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| Year : 2016 | Volume
: 1
| Issue : 1 | Page : 9-11 |
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A Case Report of Neuroleptic Malignant Syndrome Following the Stoppage of Anti Parkinsonian Medication
BA Yakasai, H Sani
Department of Internal Medicine, BarauDikko Teaching Hospital, Kaduna State University, Kaduna, Nigeria
Correspondence Address:
B A Yakasai
Department of Internal Medicine, BarauDikko Teaching Hospital, Kaduna State University, Kaduna, Nigeria
 Source of Support: None, Conflict of Interest: None
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Background: Neuroleptic Malignant Syndrome (NMS) is a rare and potentially fatal complication seen in Parkinson's disease (PD), mostly due a reduction of anti-Parkinson's medication. The mortality rate is up to 4percent.
Case: We report a case of 73 years old man who has been receiving treatment for PD since 2001 with Sinemet, bromocriptine and benzhexol ( artane). On subsequent follow up visits at BarauDikko Teaching Hospital (BDTH), Kaduna State University (KASU), the dosage of the Sinemet was increased to 250 mg. However, despite the increase
in the dosage of Sinemet, his condition was not improving much, as such we decided to add Bromocriptine 10 mg tid. A week after introduction of bromocriptine, the patient started having an "ON and Off Phenomenon" This prompted the immediate removal of the bromocriptine from his medication. A few days after the removal of bromocriptine he developed acute fever with a generalized body stiffness, excess salivation and confusion.
Conclusion: The result of blood tests and physical examination indicated a strong evidence of a NMS. |
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