• Users Online: 389
  • Print this page
  • Email this page
CASE REPORT
Year : 2016  |  Volume : 1  |  Issue : 1  |  Page : 9-11

A Case Report of Neuroleptic Malignant Syndrome Following the Stoppage of Anti Parkinsonian Medication


Department of Internal Medicine, BarauDikko Teaching Hospital, Kaduna State University, Kaduna, Nigeria

Correspondence Address:
B A Yakasai
Department of Internal Medicine, BarauDikko Teaching Hospital, Kaduna State University, Kaduna, Nigeria

Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Background: Neuroleptic Malignant Syndrome (NMS) is a rare and potentially fatal complication seen in Parkinson's disease (PD), mostly due a reduction of anti-Parkinson's medication. The mortality rate is up to 4percent. Case: We report a case of 73 years old man who has been receiving treatment for PD since 2001 with Sinemet, bromocriptine and benzhexol ( artane). On subsequent follow up visits at BarauDikko Teaching Hospital (BDTH), Kaduna State University (KASU), the dosage of the Sinemet was increased to 250 mg. However, despite the increase in the dosage of Sinemet, his condition was not improving much, as such we decided to add Bromocriptine 10 mg tid. A week after introduction of bromocriptine, the patient started having an "ON and Off Phenomenon" This prompted the immediate removal of the bromocriptine from his medication. A few days after the removal of bromocriptine he developed acute fever with a generalized body stiffness, excess salivation and confusion. Conclusion: The result of blood tests and physical examination indicated a strong evidence of a NMS.


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2157    
    Printed105    
    Emailed1    
    PDF Downloaded18    
    Comments [Add]    

Recommend this journal